Generalized pseudocalcium deposition-like lesion in the arteriolar wall of 48-year-old male who died of cytomegalic inclusion body disease was studied. The authors performed a histopathological examination on the salivary glands which showed remarkable changes than any other part of organs in the body, and compared it with the same kind of lesions of the arterioles in oder to determine the substance of pseudocalcium depositiorlike lesion. As the result, this lesion was not illcluded in previously reported vascular lesions as regards a characteristics of staining and location. The authors postulated that cytomegalic inclusion body disease was effecting as a trigger to the formation of the pseudocalcium deposition-like lesion.