The clinical outcomes of dinoprostone vaginal insert and mechanical methods for cervical ripening were compared retrospectively. The duration of labor and the time taken for hospital discharge were significantly shorter in the vaginal group than in the mechanical group. Mothers in the vaginal group had a significantly higher percentage of deliveries within 24 hours of vaginal insertion of dinoprostone than those in the mechanical group. In cases in which labor was induced at 37 or 38 weeks’ gestation due to maternal complications, there were no cases in either group in which use was discontinued due to worsening complications. Moreover, the time taken for hospital discharge was significantly shorter in the vaginal group, indicating the usefulness of dinoprostone vaginal insert in patients with maternal complications. On the other hand, uterine tachysystole and fetal dysfunctions may occur while administering dinoprostone vaginal inserts; therefore, careful management and compliance with the directions for use is necessary.