化学放射線療法が奏効した食道癌肉腫の1例

中原 史雄; 藤澤 美亜; 鈴木 孝良; 川嶌 洋平; 津田 真吾; 鶴谷 康太; 水上 創; 中村 淳; 仁品 玲子; 中島 貴之; 大北 一郎; 白倉 克也; 五十嵐 宗喜; 小池 潤; 松嶋 成志; 峯 徹哉

doi:10.11641/pde.82.1_100

A case of carcinosarcoma of the esophagus treated by chemoradiotherapy

Fumio Nakahara, Mia Fujisawa, Takayoshi Suzuki, Yohei Kawashima, Shingo Tsuda, Kota Tsuruya, Hajime Mizukami, Jun Nakamura, Ryoko Nishina, Takayuki Nakajima, Ichiro Okita, Katsuya Shirakura, Muneki Igarashi, Jun Koike, Masashi Matsushima, Tetsuya Mine

Author information

Fumio Nakahara
Department of Gastroenterological Medicine, Tokai University School of Medicine
Mia Fujisawa
Department of Gastroenterological Medicine, Tokai University School of Medicine
Takayoshi Suzuki
Department of Gastroenterological Medicine, Tokai University School of Medicine
Yohei Kawashima
Department of Gastroenterological Medicine, Tokai University School of Medicine
Shingo Tsuda
Department of Gastroenterological Medicine, Tokai University School of Medicine
Kota Tsuruya
Department of Gastroenterological Medicine, Tokai University School of Medicine
Hajime Mizukami
Department of Gastroenterological Medicine, Tokai University School of Medicine
Jun Nakamura
Department of Gastroenterological Medicine, Tokai University School of Medicine
Ryoko Nishina
Department of Gastroenterological Medicine, Tokai University School of Medicine
Takayuki Nakajima
Department of Gastroenterological Medicine, Tokai University School of Medicine
Ichiro Okita
Department of Gastroenterological Medicine, Tokai University School of Medicine
Katsuya Shirakura
Department of Gastroenterological Medicine, Tokai University School of Medicine
Muneki Igarashi
Department of Gastroenterological Medicine, Tokai University School of Medicine
Jun Koike
Department of Gastroenterological Medicine, Tokai University School of Medicine
Masashi Matsushima
Department of Gastroenterological Medicine, Tokai University School of Medicine
Tetsuya Mine
Department of Gastroenterological Medicine, Tokai University School of Medicine

JOURNAL FREE ACCESS

2013 Volume 82 Issue 1 Pages 100-101

DOI https://njjn-jsjc-gov-cn-s-1416.res.gxlib.org.cn:443/rwt/1416/https/MSYXTLUQPJUB/10.11641/pde.82.1_100

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Abstract

Carcinosarcoma of the esophagus is a relatively rare malignant neoplasm. Esophagectomy with regional lymph node dissection has often been performed to cure patients with this condition. Chemoradiotherapy has also been used to treat unresectable carcinosarcoma. This report describes an 83-year-old man with carcinosarcoma of the esophagus who was treated with chemoradiotherapy. Barium swallow examination showed an elevated lesion─measuring about 80 mm in diameter─in the thoracic and abdominal esophagus. Endoscopic examination revealed a type 2 tumor ＋IIb lesion in the esophagus. Histological analysis of a biopsy from the tumor demonstrated a carcinosarcoma. CT scan showed no evidence of lymph node swelling or distant metastasis. Thus, the clinical diagnosis was T3N0M0 cStage II. The patient declined surgery. Chemoradiotherapy─consisting of 5-FU and CDDP with radiotherapy of 60 Gy─was administered to the patient. He did not undergo additional chemotherapy, as he and his family wished to cease therapy. Endoscopic examination revealed that the carcinosarcoma had decreased in size.
The patient has now been alive for 15 months since initiation of treatment.

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