Radiation Environment and Medicine
Online ISSN : 2432-163X
Print ISSN : 2423-9097
ISSN-L : 2423-9097
Volume 5, Issue 1
Radiation Environment and Medicine
Displaying 1-12 of 12 articles from this issue
Special Contribution
Review
  • Gerald M Kendall, Mark P Little, Richard Wakeford, Kathryn J Bunch, Jo ...
    2016 Volume 5 Issue 1 Pages 27-30
    Published: March 11, 2016
    Released on J-STAGE: April 20, 2023
    JOURNAL FREE ACCESS

    Studies of natural radiation and childhood cancer must be very large if they are to have sufficient power to detect the very small radiation effects expected. Conventional interviewbased case control studies with a sufficiently large number of study subjects would be exceptionally expensive and would also be liable to bias which might lead to confounding that would dominate the results of the study. Record based studies, in which cases and controls are drawn from existing registers, have the potential to be large enough and to avoid the risk of bias. However, they will not have interview-based information on factors such as Socioeconomic Status, nor will they have direct measurements of radiation levels in the homes of study subjects. A large record-based case control study from Great Britain is reviewed here in the context of such case-control studies generally. This study has detected a statistically significant association between indoor gamma ray exposures and the incidence of childhood leukaemia. The risk factor was compatible with that extrapolated from higher dose studies, in particular those of the Atomic Bomb Survivors.

    Download PDF (542K)
  • Gerald M Kendall, John F Bithell, Kathryn J Bunch, Gerald J Draper, Ma ...
    2016 Volume 5 Issue 1 Pages 31-39
    Published: March 11, 2016
    Released on J-STAGE: April 20, 2023
    JOURNAL FREE ACCESS

    A media report in 1983 drew attention to high levels of childhood leukaemia around the Sellafield nuclear reprocessing plant. This prompted investigations around other nuclear installations, some of which suggested other “clusters”, though Sellafield remained the most striking. Many studies over more than 30 years have investigated possible reasons for such clusters. Inevitably attention was first directed at radiation linked with activities at the plant. However, it was found that doses from accidental and planned releases were too low to account for the observed levels of childhood leukaemia. Various other mechanisms involving radiation have been investigated and have also been discounted. While no clear explanation for the Sellafield cluster has been found, perhaps the most plausible remaining hypothesis involves “population mixing” in which an infection is spread to susceptible individuals and, in rare cases, results in leukaemia.

    Download PDF (598K)
  • Mati Ur Rehman, Paras Jawaid, Takashi Kondo*
    2016 Volume 5 Issue 1 Pages 40-45
    Published: March 11, 2016
    Released on J-STAGE: April 20, 2023
    JOURNAL FREE ACCESS

    Radiation therapy (RT) is an approved, most widely used strategy for the treatment and control of cancer progression but its successful application solely depends on the radiosensitivity of tumor cells and tolerance of normal tissue. To overcome this, very often radiation therapy is combined with radiosensitizing agents. Recently, due to the advancement in the field of nanotechnology, metal nanoparticles have been discovered as the novel radiosensitizers such as gold nanoparticles (GNPs). In contrast, some nanoparticles of noble metals like platinum nanoparticles (nano-Pts) act as radioprotectors and inhibit radiation-induced cell death. This review will summarize the latest findings on the 1) radiosensitizing effects of GNPs, 2) effects of platinum nanoparticles on inflammation and radiation-induced cell death.

    Download PDF (936K)
Regular Article
Note
  • Saïdou, Shinji Tokonami, Ele Abiama Patrice
    2016 Volume 5 Issue 1 Pages 53-58
    Published: March 11, 2016
    Released on J-STAGE: April 20, 2023
    JOURNAL FREE ACCESS

    The present paper summarizes the findings of the preliminary studies carried out in the uranium and thorium bearing regions of Cameroon. It also underlines future prospects for extensive measurements of natural radioactivity for a better radiation dose assessment to the public. After soil and foodstuff sampling, α- and γ- spectrometry were used to determine activity concentrations of natural radionuclides in these samples. Electret Ionization Chambers (EPERM) were deployed in Poli and Lolodorf to measure radon in houses. 20% of dwellings in Poli and 50% in Lolodorf have radon concentrations higher than 300 Bq m-3. Passive integrated radon thoron discriminative detectors (RADUET) were used only in the high natural radiation areas of Lolodorf to measure simultaneously indoor radon and thoron. 30% of houses have thoron concentrations above 300 Bq m-3. Effective dose to the public and annual excess risk for radon-induced lung cancer of each of the studied regions are higher than the world average values. Difference is mainly attributed to indoor radon exposure. Taking into account of the limited number of analyzed samples and surveyed dwellings, some conclusions should cautiously be considered.

    Download PDF (2515K)
Report
feedback
Top